According to the study, the virus infects cells more easily than when it appeared in China last year. It could be more contagious. Variant of SAR
According to the study, the virus infects cells more easily than when it appeared in China last year. It could be more contagious.
The variant of SARS-CoV-2, which dominates the world today, infects cells more easily than the one that originally appeared in China. With a result that makes it possibly the most contagious from human to human, although that has yet to be confirmed, according to a study published Thursday in the journal Cell.
“We don’t know yet whether a person is worse off with it or not,” commented Anthony Fauci, director of the Institute of Infectious Diseases in the US journal Jama. “The virus seems to replicate better and may be more transmissible, but we’re still in the process of trying to confirm that. But there are very good genetic viruses that are working on it.”
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After leaving China and arriving in Europe, the variant of the new coronavirus, which constantly mutates like a virus, became dominant, and it was this European version that was then installed in the United States of America. The variant, called D614G, refers to a single letter in the virus’s DNA, at a site that controls the point at which it enters human cells.
genetic mutation stalked
Researchers around the world are following the genetic mutations of the coronavirus, which have found the sequencing of the virus’s genome and are sharing it on the international database, GISAID, a treasure trove of more than 30,000 sequences to date.
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Researchers of the new study from Sheffield and Duke universities and Los Alamos National Laboratory founded in April because D614G was now dominant and then said, with some alarm, that the mutation made the virus more transmissible.” They put their results online on the preprints website. scientists. But that claim has been criticized because the team did not show that the mutation itself was the cause of the dominance; it is possible that other factors or chance favored it. The scientists therefore conducted further research and experiments, at the request of Cell editors.
First, they analyzed data from 999 patients in the UK hospitalized for Covid-19 and noticed that those with the variant had more virus particles in them, but this did not change the severity of their disease – which is encouraging news. On the other hand, laboratory experiments showed that the variant was still three to six times more capable of infecting human cells. “It seems likely that this is a more capable virus,” said Erica Ollmann Saphire, who conducted one of these experiments at the La Jolla Institute for Immunology.
It is not necessarily “transferable” between people.
But everything is “probable”: an in vitro experiment cannot reproduce the real dynamics of a pandemic. The conclusion is stricter so that if the currently circulating coronavirus is probably the “most contagious”, it is not necessarily the most “transmissible” among humans.
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In any case, Nathan Grubaugh of Yale University and his colleagues write in a separate article, “this variant is now a pandemic.” “D614G should not change our containment measures or make individual infections worse,” says Nathan Grubaugh.
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“COVID-19”, the new coronavirus
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“We are witnessing scientific work in real time: this is an interesting discovery that potentially affects millions of people, but for which we do not yet know the final effect. We discovered the virus six months ago, and we will learn many more things in the next six months.”
Updated date: July 3, 2020, 5:58 a.m
Categories: Optical Illusion
Source: newstars.edu.vn