The steroid reduces by one third the mortality in patients with the most severely affected, according to new results. The british services of health will use it
The steroid reduces by one third the mortality in patients with the most severely affected, according to new results. The british services of health will use it as soon as Tuesday.
Despite a return to near normal after the déconfinements in many countries, as in France, the pandemic Covid-19 is not complete. Some countries, like China, fear is already a second wave response to the appearance of new cases. And for the time being, there is no vaccine or treatment are marketed. Even if we talk about a lot of the chlroroquine, treatment controversial defended by the Pr Didier Raoult, other drugs are promising. This is the case of dexamethasone, according to the first results of a large clinical trial Recovery published on Tuesday. The Express makes the point.
what is dexamethasone ?
first thing’s First, this treatment is already known. It is a medication in the family of steroids. It is used in many indications for its anti-inflammatory effect powerful. It is also prescribed for patients with cancer, in chemotherapy.
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According to the Vidal reference guide for health professionals, corticosteroids, synthetic – including the dexamethasone – decreased (high-dose) immune response. Their metabolic effect and sodium retention is less than that of hydrocortisone (…) In ophthalmology, it has been demonstrated that dexamethasone, a corticosteroid powerful, could suppress inflammation by inhibiting edema, fibrin deposition, leaking capillaries and the migration, phagocytic inflammatory response.”
Why is it promising ?
“The dexamethasone is the first drug which we observe that it improves the survival in case of Covid-19″, said in a press release the officials of the trial british Recovery. According to the first results of a large clinical trial – qualified Tuesday of”major step forward” -, dexamethasone, reduces by one third the mortality in patients with the most severely affected by the Covid-19.
According to the officials of the trial, “for each group of eight patients placed under artificial ventilation, a death could be avoided”. “This is a major breakthrough in the search for new ways to treat the sick, the Covid”, was delighted in another press release, professor Stephen Powis, medical director of the NHS, the public health service of the uk.
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“The benefit in terms of survival is important for patients who are sick enough to need oxygen, for which the dexamethasone should become the basic salary,” said one of the leaders of the trial Recovery, professor Peter Horby, of the university of Oxford.
In the framework of the test Recovery, 2104 patients have received this treatment (orally or intravenously) for 10 days. In comparing it to 4321 with other patients who had not received, the researchers have determined that the treatment reduced by one third the mortality in patients under artificial ventilation. In addition, mortality has been reduced by one fifth in patients less severely ill, who administered oxygen through a face mask without intubation. In contrast, the treatment showed no benefit for patients who did not require respiratory assistance.
Can it be used quickly ?
Yes, this is the advantage of this treatment. “The dexamethasone is not expensive, already marketed and can be immediately used to save lives around the world,” said professor Peter Horby. The british services health (NHS) will, moreover, use it as soon as Tuesday to treat the disease, announced the Health minister, Matt Hancock.
“We are working with the NHS to include the dexamethasone treatment standard anti-Covid-19 from this afternoon,” said Matt Hancock in a video posted on his Twitter account. Furthermore, he stated that the Uk had 200 000 treatments ready-to-use stored since march.
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“Covid-19”, the new coronavirus
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Date Of Update: 16 June 2020, 22:58
Categories: Optical Illusion
Source: newstars.edu.vn