The Solidarity and Discovery trials dropped out of treatment and lopinavir/ritonavir was deemed ineffective. They no longer carry it in any medication,
The Solidarity and Discovery trials dropped out of treatment and lopinavir/ritonavir was deemed ineffective. They don’t have that anymore with one drug, remdesivir.
The science of faucets. The list of possible drugs against Covid-19 continues to shrink: after hydroxychloroquine, the European Solidarity and Discovery clinical trials have also abandoned the treatment, and lopinavir/ritonavir is considered ineffective and has suspected adverse effects. Following this decision, these two trials will now focus on more than one drug, remdesivir, which is only marketed under the condition of the European Union.
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the combination of two antiviral drugs, lopinavir and ritonavir, used against the AIDS virus (and marketed under the name Kaletra), was already discontinued at the end of June by another major clinical trial, British Recovery.
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Discovery highlighted the “high frequency of side effects”
The decision was made jointly by the WHO (World Health Organization) on Saturday for the Solidarity trial organized by the responsible French trial partner, Discovery. At the same time, the WHO definitively supported the abolition of hydroxychloroquine, decided on June 17.
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“Preliminary results show that hydroxychloroquine and lopinavir/ritonavir do not reduce or do not reduce mortality in patients hospitalized for covid-19 compared to standard care,” the WHO said in a press release.
In addition, the Discovery trial highlighted a “significantly higher frequency of serious adverse effects on renal function in patients treated with lopinavir/ritonavir, according to a press release from Insermo, the French research institute organizing this trial. This is especially the case “in patients hospitalized in the intensive care unit. “, says Inserm. According to the WHO and Inserm, all these results will be published in a scientific journal.
There is no treatment that stands out
Although dozens of treatments against Covid-19 are being evaluated around the world, none to date have shown remarkable efficacy, with the exception of the steroid dexamethasone, for the most affected patients.
According to the results of the Recovery test, dexamethasone reduces mortality in the most severe patients, those who are on mechanical ventilation. Remdesivir, for its part, received a conditional marketing authorization within the EU on July 3, issued by the European Commission.
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“COVID-19”, the new coronavirus
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An American study showed that this antiviral drug, originally developed against Ebola hemorrhagic fever, slightly reduced recovery time for hospitalized Covid-19 patients (from 15 to 11 days on average). On the other hand, there are no proven benefits in terms of mortality reduction.
Date updated: Jul 7, 2020, 04:58
Categories: Optical Illusion
Source: newstars.edu.vn