Hydroxychloroquine : The Lancet takes his distances with his controversial paper

The study in question, which pointed to an increased risk of death, has led in the world to the interruption of clinical trials with hydroxychloroquine. Here’

The study in question, which pointed to an increased risk of death, has led in the world to the interruption of clinical trials with hydroxychloroquine.

Here’s some news that should delight Didier Raoult. The prestigious medical journal The Lancet has taken its distances with the study of the criticism she has published on the hydroxychloroquine – promoted by the famous professor – recognizing in a formal warning that “important questions” arise about it. The Lancet wishes to “alert readers to the fact that scientific issues have been brought to (his) attention” to the subject of this study, which is currently the subject of an audit initiated by its authors.

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This warning was issued Tuesday evening in the form of an “expression of concern” (“expression of concern”), a formal statement used by scientific journals to indicate that a study is potentially problematic. If an “expression of concern” is not as heavy of consequences as a withdrawal, pure and simple, which means the withdrawal of the publication, it is still of a nature to cast doubt on scientific work.

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Doubts of many researchers since the publication

The study in question was led into the world to the interruption of clinical trials with hydroxychloroquine, since it concludes that this drug, associated or not with a macrolide – an antibiotic such as azithromycin, is not beneficial to the sick of the Covid-19 hospitalized, and can even be detrimental, or even fatal. Published may 22 in The Lancet, this work is based on the data of 96 000 patients hospitalized between December and April in 671 hospitals and compare the state of those who have received the treatment to that of patients who have not had.

According to the authors, 9.3% of those receiving standard care – without hydroxychloroquine – died in hospital, compared with 17% of patients on chloroquine or hydroxychloroquine, and 23% when they were receiving a macrolide.

OUR MAINTENANCE >> Didier Raoult : “in The beginning, I had doubts about the chloroquine, but more now”

In the wake of its publication, many researchers have expressed their doubts about the study, including scientists who had also criticized studies of the Pr. Raoult. In an open letter published on the 28th of may, dozens of scientists around the world emphasize that the careful examination of the study in the Lancet raises “to both of the concerns related to methodology and to the integrity of the data”.

A study still defended by its authors

These data come from Surgisphere, which presents itself as a society of analysis of health data, based in the United States. The company has recognized some of the errors, but has refused to make its data public, citing “agreements of use” by preventing. The study has also been attacked with virulence by the defenders of the hydroxychloroquine, the first of which the French researcher Didier Raoult.

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After you have already called the study “half-assed”, he believed that it had been done by “nickel plated feet”, in a video put online on Tuesday. For their part, the authors, Dr. Mandeep Mehra and his colleagues, defending their study. “We are proud to contribute to the work on the Covid-19″ in this period of”uncertainty”, had told AFP on may 29, one of them, Sapan Desai, owner of Surgisphere.

Date Of Update: 03 June 2020, 11:58

Categories: Optical Illusion
Source: newstars.edu.vn

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